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Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene

Activation by growth factors of the Ras-dependent signaling cascade results in the induction of p90 ribosomal S6 kinases (p90(rsk)). These are translocated into the nucleus upon phosphorylation by mitogen-activated protein kinases, with which p90(rsk) are physically associated in the cytoplasm. In h...

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Bibliografiska uppgifter
Huvudupphovsmän: De Cesare, Dario, Jacquot, Sylvie, Hanauer, André, Sassone-Corsi, Paolo
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1998
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC22809/
https://ncbi.nlm.nih.gov/pubmed/9770464
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