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Transcriptional repression of the c-fos gene by YY1 is mediated by a direct interaction with ATF/CREB.

Transcriptional activation of the mouse c-fos gene by the adenovirus 243-amino-acid E1A protein requires a binding site for transcription factor YY1 located at -54 of the c-fos promoter. YY1 normally represses transcription of c-fos, and this repression depends on the presence of a cyclic AMP (cAMP)...

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Autors principals: Zhou, Q, Gedrich, R W, Engel, D A
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC189172/
https://ncbi.nlm.nih.gov/pubmed/7769693
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