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Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S

Endoglycosidase S (EndoS) is a bacterial endo-β-N-acetylglucosaminidase that specifically catalyzes the hydrolysis of the β-1,4 linkage between the first two N-acetylglucosamine residues of the biantennary complex-type N-linked glycans of IgG Fc regions. It is used for the chemoenzymatic synthesis o...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Trastoy, Beatriz, Klontz, Erik, Orwenyo, Jared, Marina, Alberto, Wang, Lai-Xi, Sundberg, Eric J., Guerin, Marcelo E.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951799/
https://ncbi.nlm.nih.gov/pubmed/29760474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04300-x
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