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Structural insights into the mechanisms and specificities of IgG-active endoglycosidases
The conserved N-glycan on Asn297 of immunoglobulin G (IgG) has significant impacts on antibody effector functions, and is a frequent target for antibody engineering. Chemoenzymatic synthesis has emerged as a strategy for producing antibodies with homogenous glycosylation and improved effector functi...
Gorde:
| Argitaratua izan da: | Glycobiology |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7476101/ https://ncbi.nlm.nih.gov/pubmed/31172182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz042 |
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