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Structural insights into the mechanisms and specificities of IgG-active endoglycosidases
The conserved N-glycan on Asn297 of immunoglobulin G (IgG) has significant impacts on antibody effector functions, and is a frequent target for antibody engineering. Chemoenzymatic synthesis has emerged as a strategy for producing antibodies with homogenous glycosylation and improved effector functi...
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| Publicat a: | Glycobiology |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7476101/ https://ncbi.nlm.nih.gov/pubmed/31172182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz042 |
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