Aire Disruption Influences the Medullary Thymic Epithelial Cell Transcriptome and Interaction With Thymocytes

The function of medullary thymic epithelial cells (mTECs) is associated with thymocyte adhesion, which is crucial for the negative selection of autoreactive thymocytes in the thymus. This process represents the root of central tolerance of self-components and prevents the onset of autoimmune disease...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Immunol
Egile Nagusiak: Speck-Hernandez, Cesar A., Assis, Amanda F., Felicio, Rafaela F., Cotrim-Sousa, Larissa, Pezzi, Nicole, Lopes, Gabriel S., Bombonato-Prado, Karina F., Giuliatti, Silvana, Passos, Geraldo A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2018
Gaiak:
Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949327/
https://ncbi.nlm.nih.gov/pubmed/29867946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00964
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