Aire Disruption Influences the Medullary Thymic Epithelial Cell Transcriptome and Interaction With Thymocytes

The function of medullary thymic epithelial cells (mTECs) is associated with thymocyte adhesion, which is crucial for the negative selection of autoreactive thymocytes in the thymus. This process represents the root of central tolerance of self-components and prevents the onset of autoimmune disease...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Speck-Hernandez, Cesar A., Assis, Amanda F., Felicio, Rafaela F., Cotrim-Sousa, Larissa, Pezzi, Nicole, Lopes, Gabriel S., Bombonato-Prado, Karina F., Giuliatti, Silvana, Passos, Geraldo A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2018
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949327/
https://ncbi.nlm.nih.gov/pubmed/29867946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00964
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller