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Update on Aire and thymic negative selection

Twenty years ago, the autoimmune regulator (Aire) gene was associated with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy, and was cloned and sequenced. Its importance goes beyond its abstract link with human autoimmune disease. Aire identification opened new perspectives to better u...

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Bibliografische gegevens
Gepubliceerd in:Immunology
Hoofdauteurs: Passos, Geraldo A., Speck‐Hernandez, Cesar A., Assis, Amanda F., Mendes‐da‐Cruz, Daniella A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721245/
https://ncbi.nlm.nih.gov/pubmed/28871661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12831
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