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Update on Aire and thymic negative selection

Twenty years ago, the autoimmune regulator (Aire) gene was associated with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy, and was cloned and sequenced. Its importance goes beyond its abstract link with human autoimmune disease. Aire identification opened new perspectives to better u...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Passos, Geraldo A., Speck‐Hernandez, Cesar A., Assis, Amanda F., Mendes‐da‐Cruz, Daniella A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721245/
https://ncbi.nlm.nih.gov/pubmed/28871661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12831
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