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Update on Aire and thymic negative selection
Twenty years ago, the autoimmune regulator (Aire) gene was associated with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy, and was cloned and sequenced. Its importance goes beyond its abstract link with human autoimmune disease. Aire identification opened new perspectives to better u...
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| Veröffentlicht in: | Immunology |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5721245/ https://ncbi.nlm.nih.gov/pubmed/28871661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12831 |
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