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Update on Aire and thymic negative selection
Twenty years ago, the autoimmune regulator (Aire) gene was associated with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy, and was cloned and sequenced. Its importance goes beyond its abstract link with human autoimmune disease. Aire identification opened new perspectives to better u...
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| Pubblicato in: | Immunology |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5721245/ https://ncbi.nlm.nih.gov/pubmed/28871661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12831 |
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