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EBI2 contributes to the induction of thymic central tolerance by promoting rapid motility of medullary thymocytes
Maturing thymocytes enter the thymic medulla, where they encounter numerous self-antigens presented by antigen presenting cells (APC). Those thymocytes that are strongly self-reactive undergo either negative selection or diversion into the regulatory T cell lineage. Although the majority of the prot...
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| Publié dans: | Eur J Immunol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5944344/ https://ncbi.nlm.nih.gov/pubmed/28741728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747020 |
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