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EBI2 contributes to the induction of thymic central tolerance by promoting rapid motility of medullary thymocytes

Maturing thymocytes enter the thymic medulla, where they encounter numerous self-antigens presented by antigen presenting cells (APC). Those thymocytes that are strongly self-reactive undergo either negative selection or diversion into the regulatory T cell lineage. Although the majority of the prot...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Ki, Sanghee, Thyagarajan, Hiran M., Hu, Zicheng, Lancaster, Jessica N., Ehrlich, Lauren I.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944344/
https://ncbi.nlm.nih.gov/pubmed/28741728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747020
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