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The Contribution of Chemokines and Migration to the Induction of Central Tolerance in the Thymus
As T cells develop, they migrate throughout the thymus where they undergo essential bi-directional signaling with stromal cells in distinct thymic microenvironments. Immature thymocyte progenitors are located in the thymic cortex. Following T cell receptor expression and positive selection, thymocyt...
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| Publicado no: | Front Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4528182/ https://ncbi.nlm.nih.gov/pubmed/26300884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00398 |
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