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Identification and characterisation of a novel heat shock protein 90 inhibitor ONO4140

Heat shock protein (Hsp) 90 is a key component of the super-chaperone complex that maintains functionally active conformation of various client proteins. Many of these client proteins regulate important nodal points in multiple signalling pathways that promote cancer cell growth and survival. Inhibi...

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Detalles Bibliográficos
Publicado en:Eur J Cancer
Main Authors: Eachkoti, Rafiqa, Reddy, M.V. Ramana, Lieu, Yen K., Cosenza, Stephen C., Reddy, E. PremKumar
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949068/
https://ncbi.nlm.nih.gov/pubmed/24835034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2014.04.017
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