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Identification and characterisation of a novel heat shock protein 90 inhibitor ONO4140
Heat shock protein (Hsp) 90 is a key component of the super-chaperone complex that maintains functionally active conformation of various client proteins. Many of these client proteins regulate important nodal points in multiple signalling pathways that promote cancer cell growth and survival. Inhibi...
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| Publié dans: | Eur J Cancer |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5949068/ https://ncbi.nlm.nih.gov/pubmed/24835034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2014.04.017 |
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