Biomarkers that Predict Sensitivity to Heat Shock Protein 90 Inhibitors (HSP90i)

PURPOSE: HSP90, a viable target for cancer treatment, mediates the maturation and stabilization of client oncoproteins. HSP90i are potentially active in a variety of tumors, but therapeutic benefit is confirmed in only a small subset. We explored potential biomarkers across multiple studies of HSP90...

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Pubblicato in:Clin Breast Cancer
Autori principali: Jhaveri, Komal, Chandarlapaty, Sarat, Iyengar, Neil, Morris, Patrick G., Corben, Adriana D, Patil, Sujata, Akram, Muzaffar, Towers, Russell, Sakr, Rita A, King, Tari A, Norton, Larry, Rosen, Neal, Hudis, Clifford, Modi, Shanu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242238/
https://ncbi.nlm.nih.gov/pubmed/26726007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clbc.2015.11.004
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