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Activity of the Heat Shock Protein 90 Inhibitor Ganetespib in Melanoma

Heat shock protein 90 (HSP90) is involved in the regulation of diverse biological processes such as cell signaling, proliferation and survival, and has been recently recognized as a potential target for cancer therapy. Ganetespib is a potent ATP competitive inhibitor of HSP90. Ganetespib downregulat...

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מידע ביבליוגרפי
Main Authors: Wu, Xinqi, Marmarelis, Melina E., Hodi, F. Stephen
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572008/
https://ncbi.nlm.nih.gov/pubmed/23418523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056134
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