Serum-free Erythroid Differentiation for Efficient Genetic Modification and High-Level Adult Hemoglobin Production

In vitro erythroid differentiation from primary human cells is valuable to develop genetic strategies for hemoglobin disorders. However, current erythroid differentiation methods are encumbered by modest transduction rates and high baseline fetal hemoglobin production. In this study, we sought to im...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mol Ther Methods Clin Dev
Hlavní autoři: Uchida, Naoya, Demirci, Selami, Haro-Mora, Juan J., Fujita, Atsushi, Raines, Lydia N., Hsieh, Matthew M., Tisdale, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948232/
https://ncbi.nlm.nih.gov/pubmed/29766032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.03.007
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky