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β-globin-expressing definitive erythroid progenitor cells generated from embryonic and induced pluripotent stem cell-derived sacs

Human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells represent a potential alternative source for red blood cell transfusion. However, when using traditional methods with embryoid bodies, ES cell-derived erythroid cells predominantly express embryonic type ε-globin, with lesser f...

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Bibliographic Details
Published in:Stem Cells
Main Authors: Fujita, Atsushi, Uchida, Naoya, Haro-Mora, Juan J., Winkler, Thomas, Tisdale, John
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892957/
https://ncbi.nlm.nih.gov/pubmed/26866725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2335
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