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High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane

Mitochondrial ATP synthase comprises a membrane embedded F(o) motor that rotates to drive ATP synthesis in the F(1) subunit. We used single-particle cryo-EM to obtain structures of the full complex in a lipid bilayer in the absence or presence of the inhibitor oligomycin, at 3.6 Å and 3.8 Å resoluti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Science
Prif Awduron: Srivastava, Anurag P., Luo, Min, Zhou, Wenchang, Symersky, Jindrich, Bai, Dongyang, Chambers, Melissa G., Faraldo-Gómez, José D., Liao, Maofu, Mueller, David M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948177/
https://ncbi.nlm.nih.gov/pubmed/29650704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aas9699
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