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Membrane plasticity facilitates recognition of the inhibitor oligomycin by the mitochondrial ATP synthase rotor
Enzymes in the respiratory chain are increasingly seen as potential targets against multi-drug resistance of human pathogens and cancerous cells. However, a detailed understanding of the mechanism and specificity determinants of known inhibitors is still lacking. Oligomycin, for example, has been kn...
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| Publicado en: | Biochim Biophys Acta Bioenerg |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176861/ https://ncbi.nlm.nih.gov/pubmed/29630891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2018.03.019 |
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