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Membrane plasticity facilitates recognition of the inhibitor oligomycin by the mitochondrial ATP synthase rotor

Enzymes in the respiratory chain are increasingly seen as potential targets against multi-drug resistance of human pathogens and cancerous cells. However, a detailed understanding of the mechanism and specificity determinants of known inhibitors is still lacking. Oligomycin, for example, has been kn...

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Publicado en:Biochim Biophys Acta Bioenerg
Autores principales: Zhou, Wenchang, Faraldo-Gómez, José D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176861/
https://ncbi.nlm.nih.gov/pubmed/29630891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2018.03.019
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