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Membrane plasticity facilitates recognition of the inhibitor oligomycin by the mitochondrial ATP synthase rotor

Enzymes in the respiratory chain are increasingly seen as potential targets against multi-drug resistance of human pathogens and cancerous cells. However, a detailed understanding of the mechanism and specificity determinants of known inhibitors is still lacking. Oligomycin, for example, has been kn...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Biochim Biophys Acta Bioenerg
Main Authors: Zhou, Wenchang, Faraldo-Gómez, José D.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176861/
https://ncbi.nlm.nih.gov/pubmed/29630891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2018.03.019
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