Fucosylated molecules competitively interfere with cholera toxin binding to host cells

Cholera toxin (CT) enters host intestinal epithelia cells, and its retrograde transport to the cytosol results in the massive loss of fluids and electrolytes associated with severe dehydration. To initiate this intoxication process, the B subunit of CT (CTB) first binds to a cell surface receptor di...

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Bibliografiske detaljer
Udgivet i:ACS Infect Dis
Main Authors: Wands, Amberlyn M., Cervin, Jakob, Huang, He, Zhang, Ye, Youn, Gyusaang, Brautigam, Chad A., Dzebo, Maria Matson, Björklund, Per, Wallenius, Ville, Bright, Danielle K., Bennett, Clay S., Wittung-Stafshede, Pernilla, Sampson, Nicole S., Yrlid, Ulf, Kohler, Jennifer J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948155/
https://ncbi.nlm.nih.gov/pubmed/29411974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00085
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