Fucose-Galactose Polymers Inhibit Cholera Toxin Binding to Fucosylated Structures and Galactose-Dependent Intoxication of Human Enteroids

[Image: see text] A promising strategy to limit cholera severity involves blockers mimicking the canonical cholera toxin ligand (CT) ganglioside GM1. However, to date the efficacies of most of these blockers have been evaluated in noncellular systems that lack ligands other than GM1. Importantly, th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Infect Dis
Prif Awduron: Cervin, Jakob, Boucher, Andrew, Youn, Gyusaang, Björklund, Per, Wallenius, Ville, Mottram, Lynda, Sampson, Nicole S., Yrlid, Ulf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2020
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227030/
https://ncbi.nlm.nih.gov/pubmed/32134631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00009
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