Fucosylated molecules competitively interfere with cholera toxin binding to host cells

Cholera toxin (CT) enters host intestinal epithelia cells, and its retrograde transport to the cytosol results in the massive loss of fluids and electrolytes associated with severe dehydration. To initiate this intoxication process, the B subunit of CT (CTB) first binds to a cell surface receptor di...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:ACS Infect Dis
Egile Nagusiak: Wands, Amberlyn M., Cervin, Jakob, Huang, He, Zhang, Ye, Youn, Gyusaang, Brautigam, Chad A., Dzebo, Maria Matson, Björklund, Per, Wallenius, Ville, Bright, Danielle K., Bennett, Clay S., Wittung-Stafshede, Pernilla, Sampson, Nicole S., Yrlid, Ulf, Kohler, Jennifer J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948155/
https://ncbi.nlm.nih.gov/pubmed/29411974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00085
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