Fucosylated molecules competitively interfere with cholera toxin binding to host cells

Cholera toxin (CT) enters host intestinal epithelia cells, and its retrograde transport to the cytosol results in the massive loss of fluids and electrolytes associated with severe dehydration. To initiate this intoxication process, the B subunit of CT (CTB) first binds to a cell surface receptor di...

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Publicado en:ACS Infect Dis
Autores principales: Wands, Amberlyn M., Cervin, Jakob, Huang, He, Zhang, Ye, Youn, Gyusaang, Brautigam, Chad A., Dzebo, Maria Matson, Björklund, Per, Wallenius, Ville, Bright, Danielle K., Bennett, Clay S., Wittung-Stafshede, Pernilla, Sampson, Nicole S., Yrlid, Ulf, Kohler, Jennifer J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948155/
https://ncbi.nlm.nih.gov/pubmed/29411974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00085
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