Caricamento...
Design, Synthesis and Evaluation of Oxazaborine Inhibitors of the NLRP3 Inflammasome
The NLRP3 inflammasome is an important regulator of the sterile inflammatory response, and its activation by host‐derived sterile molecules leads to the intracellular activation of caspase‐1, processing of the pro‐inflammatory cytokines interleukin‐1β (IL‐1β)/IL‐18, and pyroptotic cell death. Inappr...
Salvato in:
| Pubblicato in: | ChemMedChem |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5947144/ https://ncbi.nlm.nih.gov/pubmed/29331080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201700731 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|