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Drugging the ‘undruggable’ cancer targets

The term ‘undruggable’ was coined to describe proteins that could not be targeted pharmacologically. However, progress is being made to ‘drug’ many of these targets, and therefore more appropriate terms might be ‘difficult to drug’ or ‘yet to be drugged’. Many desirable targets in cancer fall into t...

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Dettagli Bibliografici
Pubblicato in:Nat Rev Cancer
Autori principali: Dang, Chi V., Reddy, E. Premkumar, Shokat, Kevan M., Soucek, Laura
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945194/
https://ncbi.nlm.nih.gov/pubmed/28643779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2017.36
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