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Drugging the ‘undruggable’ cancer targets

The term ‘undruggable’ was coined to describe proteins that could not be targeted pharmacologically. However, progress is being made to ‘drug’ many of these targets, and therefore more appropriate terms might be ‘difficult to drug’ or ‘yet to be drugged’. Many desirable targets in cancer fall into t...

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Detalhes bibliográficos
Publicado no:Nat Rev Cancer
Main Authors: Dang, Chi V., Reddy, E. Premkumar, Shokat, Kevan M., Soucek, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945194/
https://ncbi.nlm.nih.gov/pubmed/28643779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2017.36
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