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Drugging the ‘undruggable’ cancer targets

The term ‘undruggable’ was coined to describe proteins that could not be targeted pharmacologically. However, progress is being made to ‘drug’ many of these targets, and therefore more appropriate terms might be ‘difficult to drug’ or ‘yet to be drugged’. Many desirable targets in cancer fall into t...

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Publicado en:Nat Rev Cancer
Autores principales: Dang, Chi V., Reddy, E. Premkumar, Shokat, Kevan M., Soucek, Laura
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945194/
https://ncbi.nlm.nih.gov/pubmed/28643779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2017.36
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