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Drugging the Undruggable: Transcription Therapy for Cancer

Transcriptional regulation is often the convergence point of oncogenic signaling. It is not surprising, therefore, that aberrant gene expression is a hallmark of cancer. Transformed cells often develop a dependency on such a reprogramming highlighting the therapeutic potential of rectifying cancer-a...

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Detalhes bibliográficos
Main Authors: Yan, Chunhong, Higgins, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529832/
https://ncbi.nlm.nih.gov/pubmed/23147197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2012.11.002
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