Cargando...
Tumor suppressor p53 links ceramide metabolism to DNA damage response through alkaline ceramidase 2
p53 mediates the DNA damage response (DDR) by regulating the expression of genes implicated in cell cycle arrest, senescence, programmed cell death (PCD), and metabolism. Herein we demonstrate that human alkaline ceramidase 2 (ACER2) is a novel transcriptional target of p53 and that its transactivat...
Gardado en:
| Publicado en: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5943524/ https://ncbi.nlm.nih.gov/pubmed/29229990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0018-y |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|