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Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response
Human cells respond to DNA damage by elevating sphingosine, a bioactive sphingolipid that induces programmed cell death (PCD) in response to various forms of stress, but its regulation and role in the DNA damage response remain obscure. Herein we demonstrate that DNA damage increases sphingosine lev...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951300/ https://ncbi.nlm.nih.gov/pubmed/26943039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7825 |
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