Maternal and fetal alkaline ceramidase 2 is required for placental vascular integrity in mice

Sphingolipids have been implicated in mammalian placental development and function, but their regulation in the placenta remains unclear. Herein we report that alkaline ceramidase 2 (ACER2) plays a key role in sustaining the integrity of the placental vasculature by regulating the homeostasis of sph...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Li, Fang, Xu, Ruijuan, Lin, Chih-Li, Low, Benjamin E., Cai, Louise, Li, Sally, Ji, Ping, Huang, Liqun, Wiles, Michael V., Hannun, Yusuf A., Obeid, Lina M., Chen, Ye, Mao, Cungui
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296754/
https://ncbi.nlm.nih.gov/pubmed/32959379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001104R
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