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Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist
Family A G protein-coupled receptors (GPCRs) control diverse biological processes and are of great clinical relevance. Their archetype rhodopsin becomes naturally light sensitive by binding covalently to the photoswitchable tethered ligand (PTL) retinal. Other GPCRs, however, neither bind covalently...
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| Publicat a: | J Am Chem Soc |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5942546/ https://ncbi.nlm.nih.gov/pubmed/29166564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07659 |
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