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Heparin inhibits intracellular Mycobacterium tuberculosis bacterial replication by reducing iron levels in human macrophages

Iron is a crucial micronutrient for both mammals and their associated pathogens, and extensive literature has shown that Mycobacterium tuberculosis (Mtb) bacilli inhibited from acquiring iron from the host are severely attenuated. In contrast, increased dietary iron concentrations or patients with h...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Abreu, Rodrigo, Essler, Lauren, Loy, Allyson, Quinn, Frederick, Giri, Pramod
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940867/
https://ncbi.nlm.nih.gov/pubmed/29740038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25480-y
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