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Siderocalin inhibits the intracellular replication of Mycobacterium tuberculosis in macrophages

Siderocalin is a secreted protein that binds to siderophores to prevent bacterial iron acquisition. While it has been shown to inhibit the growth of Mycobacterium tuberculosis (M.tb) in extracellular cultures, its effect on this pathogen within macrophages is not clear. Here, we show that siderocali...

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Detalhes bibliográficos
Main Authors: Johnson, Erin E., Srikanth, Chittur V., Sandgren, Andreas, Harrington, Lynne, Trebicka, Estela, Wang, Lijian, Borregaard, Niels, Murray, Megan, Cherayil, Bobby J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822896/
https://ncbi.nlm.nih.gov/pubmed/19863663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1574-695X.2009.00622.x
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