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Immune Interference in Mycobacterium tuberculosis Intracellular Iron Acquisition through Siderocalin Recognition of Carboxymycobactins

The innate immune system, antibacterial protein Siderocalin (Scn) binds ferric carboxymycobactin (CMB) and also several catecholate siderophores. While the recognition of catecholates by Scn has been thoroughly investigated, the binding interactions of Scn with the full spectrum of CMB isoforms have...

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Detalhes bibliográficos
Main Authors: Hoette, Trisha M., Clifton, Matthew C., Zawadzka, Anna M., Holmes, Meg A., Strong, Roland K., Raymond, Kenneth N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241878/
https://ncbi.nlm.nih.gov/pubmed/21978368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200331g
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