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The Role of Electrostatics in Siderophore Recognition by the Immunoprotein Siderocalin1
Iron is required for virulence of most bacterial pathogens, many of which rely on siderophores, small-molecule chelators, to scavenge iron in mammalian hosts. As an immune response, the human protein Siderocalin binds both apo and ferric siderophores in order to intercept delivery of iron to the bac...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778733/ https://ncbi.nlm.nih.gov/pubmed/19053425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8074665 |
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