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The Role of Electrostatics in Siderophore Recognition by the Immunoprotein Siderocalin1

Iron is required for virulence of most bacterial pathogens, many of which rely on siderophores, small-molecule chelators, to scavenge iron in mammalian hosts. As an immune response, the human protein Siderocalin binds both apo and ferric siderophores in order to intercept delivery of iron to the bac...

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Autors principals: Hoette, Trisha M., Abergel, Rebecca J., Xu, Jide, Strong, Roland K., Raymond, Kenneth N.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778733/
https://ncbi.nlm.nih.gov/pubmed/19053425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8074665
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