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Siderocalin inhibits the intracellular replication of Mycobacterium tuberculosis in macrophages

Siderocalin is a secreted protein that binds to siderophores to prevent bacterial iron acquisition. While it has been shown to inhibit the growth of Mycobacterium tuberculosis (M.tb) in extracellular cultures, its effect on this pathogen within macrophages is not clear. Here, we show that siderocali...

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Autors principals: Johnson, Erin E., Srikanth, Chittur V., Sandgren, Andreas, Harrington, Lynne, Trebicka, Estela, Wang, Lijian, Borregaard, Niels, Murray, Megan, Cherayil, Bobby J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822896/
https://ncbi.nlm.nih.gov/pubmed/19863663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1574-695X.2009.00622.x
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