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Heparin inhibits intracellular Mycobacterium tuberculosis bacterial replication by reducing iron levels in human macrophages

Iron is a crucial micronutrient for both mammals and their associated pathogens, and extensive literature has shown that Mycobacterium tuberculosis (Mtb) bacilli inhibited from acquiring iron from the host are severely attenuated. In contrast, increased dietary iron concentrations or patients with h...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Abreu, Rodrigo, Essler, Lauren, Loy, Allyson, Quinn, Frederick, Giri, Pramod
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940867/
https://ncbi.nlm.nih.gov/pubmed/29740038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25480-y
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