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Protection by anti-viral memory CD8 T-cells requires rapidly produced antigen in large amounts()
Numerous attempts to produce anti-viral vaccines by harnessing memory CD8-T cells have failed. A barrier to progress is that we do not know what makes an antigen a viable target of protective CD8 T-cell memory. We found that in mice susceptible to lethal mousepox (the mouse homolog of human smallpox...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940544/ https://ncbi.nlm.nih.gov/pubmed/29643193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701568 |
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