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Memory CD8(+) T cells are gatekeepers of the lymph node draining the site of viral infection

It is uncertain how immunity protects against systemic viral diseases. Here, we demonstrate that in the absence of persistent virus, not only antibodies but also recall responses by long-lived memory CD8(+) T cells prevent mousepox, a disease caused by ectromelia virus, a close relative of the virus...

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Autors principals: Xu, Ren-Huan, Fang, Min, Klein-Szanto, Andres, Sigal, Luis J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904153/
https://ncbi.nlm.nih.gov/pubmed/17578922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701822104
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