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The Initial Draining Lymph Node Primes the Bulk of the CD8 T Cell Response and Influences Memory T Cell Trafficking after a Systemic Viral Infection

Lymphocytic choriomeningitis virus (LCMV) causes a systemic infection in mice with virus replication occurring in both peripheral tissues and secondary lymphoid organs. Because of the rapid systemic dissemination of the virus, the secondary lymphoid organs responsible for the induction of the LCMV-s...

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Autori principali: Olson, Matthew R., McDermott, Daniel S., Varga, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516554/
https://ncbi.nlm.nih.gov/pubmed/23236277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003054
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