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CD4(+) T Cell Help Is Dispensable for Protective CD8(+) T Cell Memory against Mousepox Virus following Vaccinia Virus Immunization

It has been shown in various infection models that CD4(+) T cell help (T(H)) is necessary for the conditioning, maintenance, and/or recall responses of memory CD8(+) T cells (CD8(M)). Yet, in the case of vaccinia virus (VACV), which constitutes the vaccine used to eradicate smallpox and is a candida...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Fang, Min, Remakus, Sanda, Roscoe, Felicia, Ma, Xueying, Sigal, Luis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301148/
https://ncbi.nlm.nih.gov/pubmed/25355885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02176-14
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