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Memory CD8(+) T Cells Specific for a Single Immunodominant or Subdominant Determinant Induced by Peptide-Dendritic Cell Immunization Protect from an Acute Lethal Viral Disease

The antigens recognized by individual CD8(+) T cells are small peptides bound to major histocompatibility complex (MHC) class I molecules. The CD8(+) T cell response to a virus is restricted to several peptides, and the magnitudes of the effector as well as memory phases of the response to the indiv...

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Detalhes bibliográficos
Main Authors: Remakus, Sanda, Rubio, Daniel, Ma, Xueying, Sette, Alessandro, Sigal, Luis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446599/
https://ncbi.nlm.nih.gov/pubmed/22740418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00981-12
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