Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression

Blood flow shapes vascular networks by orchestrating endothelial cell behavior and function. How endothelial cells read and interpret flow-derived signals is poorly understood. Here, we show that endothelial cells in the developing mouse retina form and use luminal primary cilia to stabilize vessel...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Vion, Anne-Clémence, Alt, Silvanus, Klaus-Bergmann, Alexandra, Szymborska, Anna, Zheng, Tuyu, Perovic, Tijana, Hammoutene, Adel, Oliveira, Marta Bastos, Bartels-Klein, Eireen, Hollfinger, Irene, Rautou, Pierre-Emmanuel, Bernabeu, Miguel O., Gerhardt, Holger
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2018
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940299/
https://ncbi.nlm.nih.gov/pubmed/29500191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706151
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