Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression

Blood flow shapes vascular networks by orchestrating endothelial cell behavior and function. How endothelial cells read and interpret flow-derived signals is poorly understood. Here, we show that endothelial cells in the developing mouse retina form and use luminal primary cilia to stabilize vessel...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Vion, Anne-Clémence, Alt, Silvanus, Klaus-Bergmann, Alexandra, Szymborska, Anna, Zheng, Tuyu, Perovic, Tijana, Hammoutene, Adel, Oliveira, Marta Bastos, Bartels-Klein, Eireen, Hollfinger, Irene, Rautou, Pierre-Emmanuel, Bernabeu, Miguel O., Gerhardt, Holger
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2018
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940299/
https://ncbi.nlm.nih.gov/pubmed/29500191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706151
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