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YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

Formation of blood vessel networks by sprouting angiogenesis is critical for tissue growth, homeostasis and regeneration. How endothelial cells arise in adequate numbers and arrange suitably to shape functional vascular networks is poorly understood. Here we show that YAP/TAZ promote stretch-induced...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Neto, Filipa, Klaus-Bergmann, Alexandra, Ong, Yu Ting, Alt, Silvanus, Vion, Anne-Clémence, Szymborska, Anna, Carvalho, Joana R, Hollfinger, Irene, Bartels-Klein, Eireen, Franco, Claudio A, Potente, Michael, Gerhardt, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814147/
https://ncbi.nlm.nih.gov/pubmed/29400648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31037
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