Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways

Vascular networks form, remodel and mature under the influence of multiple signals of mechanical or chemical nature. How endothelial cells read and interpret these signals, and how they integrate information when they are exposed to both simultaneously is poorly understood. Here, we show using flow-...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Vion, Anne-Clémence, Perovic, Tijana, Petit, Charlie, Hollfinger, Irene, Bartels-Klein, Eireen, Frampton, Emmanuelle, Gordon, Emma, Claesson-Welsh, Lena, Gerhardt, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7960671/
https://ncbi.nlm.nih.gov/pubmed/33737879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.623769
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