Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways

Vascular networks form, remodel and mature under the influence of multiple signals of mechanical or chemical nature. How endothelial cells read and interpret these signals, and how they integrate information when they are exposed to both simultaneously is poorly understood. Here, we show using flow-...

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Detalles Bibliográficos
Publicado en:Front Physiol
Autores principales: Vion, Anne-Clémence, Perovic, Tijana, Petit, Charlie, Hollfinger, Irene, Bartels-Klein, Eireen, Frampton, Emmanuelle, Gordon, Emma, Claesson-Welsh, Lena, Gerhardt, Holger
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7960671/
https://ncbi.nlm.nih.gov/pubmed/33737879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.623769
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