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Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine-tuning

How developing vascular networks acquire the right balance of arteries, veins and lymphatic vessels to efficiently supply and drain tissues is poorly understood. In zebrafish embryos, the robust and regular 50:50 global balance of intersegmental veins and arteries that form along the trunk prompts t...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Geudens, Ilse, Coxam, Baptiste, Alt, Silvanus, Gebala, Véronique, Vion, Anne-Clémence, Meier, Katja, Rosa, Andre, Gerhardt, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737902/
https://ncbi.nlm.nih.gov/pubmed/31375478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.181024
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