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Spliceosome profiling visualizes operations of a dynamic RNP at nucleotide resolution
Tools to understand how the spliceosome functions in vivo have lagged behind advances in its structural biology. Here, methods are described to globally profile spliceosome-bound pre-mRNA, intermediates and spliced mRNA at nucleotide resolution. These tools are applied three yeast species that span...
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| Publicado no: | Cell |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940017/ https://ncbi.nlm.nih.gov/pubmed/29727661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.03.020 |
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