A Non-Dicer RNase III and Four Other Novel Factors Required for RNAi-Mediated Transposon Suppression in the Human Pathogenic Yeast Cryptococcus neoformans

The human pathogenic yeast Cryptococcus neoformans silences transposable elements using endo-siRNAs and an Argonaute, Ago1. Endo-siRNAs production requires the RNA-dependent RNA polymerase, Rdp1, and two partially redundant Dicer enzymes, Dcr1 and Dcr2, but is independent of histone H3 lysine 9 meth...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Burke, Jordan E., Longhurst, Adam D., Natarajan, Prashanthi, Rao, Beiduo, Liu, John, Sales-Lee, Jade, Mortensen, Yasaman, Moresco, James J., Diedrich, Jolene K., Yates, John R., Madhani, Hiten D.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2019
Fag:
Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643885/
https://ncbi.nlm.nih.gov/pubmed/31092606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400330
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